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Because Valium has a long half-life and, crucially, produces active metabolites with even longer half-lives that accumulate in the body and provide a sustained, gentle, and slowly waning level of GABA-A receptor occupancy, the decline in central nervous system inhibition as the Valium dose is slowly reduced over many months is far more gradual, predictable, and physiologically forgiving than would be the case with a direct taper of the Klonopin. The therapeutic goal is not to eliminate anxiety, which is a normal and adaptive human emotion, but to reduce its chronic, dysfunctional, and debilitating surplus to a level that is manageable and that no longer erodes the patient's quality of life or impairs their functional capacity. For the patient in the United States or Canada who is accustomed to the relief provided by a 1 mg dose of Ativan for acute anxiety, the inadvertent substitution of a 1 mg dose of Klonopin would represent a significant and potentially dangerous escalation in their effective benzodiazepine load, precipitating a state of profound, unintended, and prolonged sedation, cognitive impairment, and psychomotor slowing. Is There An Over The Counter Drug Like Adderall at Discounted Rates. The 1 mg tablet of Klonopin, for this individual, is a tool of functional restoration, a pharmacologic foundation upon which they can rebuild a life that was previously constricted and impoverished by the unpredictable tyranny of their disorder.
The specific question of whether clonazepam can make an individual "more depressed" touches upon the very same neurobiological mechanisms that can cause depression in the first place, and it is a phenomenon that is both clinically recognized and deeply troubling for the patient who experiences it. For the garden-variety chronic insomnia, however, the gold-standard and truly "good" treatment is not a benzodiazepine, but rather Cognitive Behavioral Therapy for Insomnia, a structured, non-pharmacologic approach that addresses the root cognitive and behavioral causes of sleeplessness and provides durable, life-long skills for restoring healthy sleep without the significant risks and long-term consequences of chronic benzodiazepine use. Klonopin For Bipolar Disorder Overnight FedEx Shipping. Within the benzodiazepine class, clonazepam is further sub-categorized as a high-potency, long-acting agent, distinctions that are of immense clinical significance.
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