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Indicated for: Major Depressive Disorder (MDD), Depressive Episodes, Unipolar Depression, Anxiety Disorder associated with Depression, Generalized Anxiety Disorder (GAD), Chronic Primary Insomnia, Secondary Insomnia (particularly with SSRI-induced sleep disturbance), Obstructive Sleep Apnea (as an adjunct to reduce arousal threshold), Painful Diabetic Neuropathy, Fibromyalgia Syndrome, Post-Traumatic Stress Disorder (PTSD) (off-label for sleep disturbances), Behavioral and Psychological Symptoms of Dementia (BPSD) (for agitation/sleep).
The emotional numbing that often accompanies and facilitates avoidance, while reducing the intensity of negative emotions, simultaneously reduces the capacity to experience positive emotions including love, joy, and the sense of connection that sustains human beings through difficult experiences. The medication trazodone has been extensively utilized in Canadian military and civilian PTSD treatment programs, with its well-established effects on sleep continuity, its suppression of REM sleep that may paradoxically reduce nightmare frequency by reducing the REM pressure that drives these intensely emotional dream experiences, and its overall anxiolytic and mood-stabilizing effects contributing to the symptom improvement that patients experience. The management of the patient who is receiving both medications should include the standard precautions that apply to each medication individually, including the avoidance of the activities requiring full alertness, such as driving, until the patient has established how the Trazodone affects them, and the adherence to the approved dosing and the duration of the Imodium therapy, with the medical evaluation if the diarrhea persists beyond two days or is accompanied by the fever, the bloody stools, or the signs of the dehydration that require more intensive medical management. Clonazepam And Trazodone. The challenge of initiating exercise during a depressive episode, when energy and motivation are at their lowest, can be addressed by starting with extremely modest goals, perhaps just a five-minute walk, and gradually increasing duration and intensity as recovery progresses.
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